Super-micro-bland particle embolization combined with RF-ablation: angiographic, macroscopic and microscopic features in porcine kidneys
Purpose: To describe angiographic, macroscopic and microscopic features of super-micro-bland particle embolization in combination with RF-ablation in kidneys. Thereby, a special focus was given on the impact of the sequence of the different procedural steps. Materials and methods: In ten pigs, super...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
European journal of radiology
Year: 2011, Volume: 81, Issue: 6, Pages: 1165-1172 |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2011.03.022 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.ejrad.2011.03.022 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0720048X11002920 
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| Author Notes: | C.M. Sommer, N. Kortes, C. Mogler, N. Bellemann, M. Holzschuh, F. Arnegger, F. Nickel, T. Gehrig, S. Zelzer, H.P. Meinzer, T. Longerich, U. Stampfl, H.U. Kauczor, B.A. Radeleff |
| Summary: | Purpose: To describe angiographic, macroscopic and microscopic features of super-micro-bland particle embolization in combination with RF-ablation in kidneys. Thereby, a special focus was given on the impact of the sequence of the different procedural steps. Materials and methods: In ten pigs, super-micro-bland particle embolization combined with RF-ablation was carried out. Super-micro-bland embolization was performed with spherical particles of very small size and tight calibration (40±10μm). In the left kidneys, RF-ablations were performed before embolization (I). In the right kidneys, RF-ablations were performed after embolization (II). The animals were killed three hours after the procedures. Angiographic (e.g. vessel architecture), macroscopic (e.g. long and short axes of the RF-ablations) and microscopic (e.g. particle distribution) study goals were defined. Results: Angiography detected almost no vessels in the center of the RF-ablations in I. In II, angiography could not define the RF-ablations. Macroscopy detected significantly larger long and short axes of the RF-ablations in II compared to I (52.2±3.2mm vs. 45.3±6.9mm [P<0.05] and 25.1±3.5mm vs. 20.0±1.9mm [P<0.01], respectively). Microscopy detected irregular particle distribution at the rim of the RF-ablations in I. In II, microscopy detected homogeneous particle distribution at the rim of the RF-ablations. Microscopy detected no particles in the center of the RF-ablations in I and II. Conclusion: The sequence of the different procedural steps of super-micro-bland particle embolization combined with RF-ablation impacts angiographic, macroscopic and microscopic features in kidneys in the acute setting. |
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| Item Description: | Available online 31 March 2011 Gesehen am 24.07.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2011.03.022 |