Takotsubo cardiomyopathy: another form of cardiorenal syndrome
Takotsubo cardiomyopathy (TC) is a life-threatening syndrome with ambiguous pathophysiology. The interdependency between heart failure and kidney failure (KF) is well established, but the influence of KF on TC outcome is not known. This single-center cohort from January 2003 to September 2015 consis...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2018
|
| In: |
Angiology
Year: 2017, Volume: 69, Issue: 2, Pages: 130-135 |
| ISSN: | 1940-1574 |
| DOI: | 10.1177/0003319717718978 |
| Online Access: | HxR, Volltext: https://doi.org/10.1177/0003319717718978
|
| Author Notes: | Verena Bill, Ibrahim El-Battrawy, Ursula Hoffmann, Darius Haghi, Jürgen Kuschyk, Martin Borggrefe, and Ibrahim Akin |
| Summary: | Takotsubo cardiomyopathy (TC) is a life-threatening syndrome with ambiguous pathophysiology. The interdependency between heart failure and kidney failure (KF) is well established, but the influence of KF on TC outcome is not known. This single-center cohort from January 2003 to September 2015 consisted of 114 consecutive patients with TC. They were divided into 2 groups according to the presence (n = 32, 29.6%) or absence (n = 76, 70.3%) of KF. The end point of this retrospective study was a composite of in-hospital events, all-cause mortality, rehospitalization due to heart failure, stroke, and recurrence of TC (mean follow-up: 5 years). Although there were no differences in baseline characteristics between patients with/without KF, we found a significantly higher mortality rate in those with KF, 1 (7.9% vs 21.8%, P < .05), 2 (11.8% vs 31.5%, P < .05), and 5 years (22.3% vs 43.7%, P < .05) after the index event. There were no differences in life-threatening arrhythmias, cardiogenic shock, cardiopulmonary resuscitation, and thromboembolic events in both groups at the index event. Patients with TC and KF have a much worse long-term prognosis. This is clinically relevant, but the mechanisms responsible remain to be determined. |
|---|---|
| Item Description: | Gesehen am 25.07.2018 Article first published online: July 10, 2017 |
| Physical Description: | Online Resource |
| ISSN: | 1940-1574 |
| DOI: | 10.1177/0003319717718978 |