Chemical basis for alteration of an intraocular lens using a femtosecond laser
The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
6 Feb 2017
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| In: |
Biomedical optics express
Year: 2017, Volume: 8, Issue: 3, Pages: 1390-1404 |
| ISSN: | 2156-7085 |
| DOI: | 10.1364/BOE.8.001390 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1364/BOE.8.001390 Verlag, kostenfrei, Volltext: https://www.osapublishing.org/boe/abstract.cfm?uri=boe-8-3-1390 
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| Author Notes: | Josef F. Bille, Johann Engelhardt, Hans-Robert Volpp, Abdelmoutalib Laghouissa, Marcus Motzkus, Zhongxiang Jiang, and Ruth Sahler |
| Summary: | The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering (CARS) microscopy. Photo-induced hydrolysis of polymeric material in aqueous media produces two hydrophilic functional groups: acid group and alcohol group. The spectral signatures identify two of the hydrophilic polar molecules as N-phenyl-4-(phenylazo)-benzenamine (C18H15N3) and phenazine-1-carboxylic acid (C13H8N2O2). The change in hydrophilicity results in a negative refractive index change in the laser-treated areas. |
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| Item Description: | Gesehen am 25.07.2018 |
| Physical Description: | Online Resource |
| ISSN: | 2156-7085 |
| DOI: | 10.1364/BOE.8.001390 |