Whole brain radiation therapy alone versus radiosurgery for patients with 1-10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial

Conventional whole brain radiotherapy (WBRT) has been established as the treatment standard in patients with cerebral metastases from small-cell lung cancer (SCLC), however, it has only modest efficacy and limited prospective data is available for WBRT as well as local treatments such as stereotacti...

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Main Authors:	Bernhardt, Denise (Author) , Hommertgen, Adriane (Author) , Schmitt, Daniela (Author) , El-Shafie, Rami (Author) , Paul, Angela (Author) , König, Laila (Author) , Mair-Walther, Johanna (Author) , Krisam, Johannes (Author) , Klose, Christina (Author) , Welzel, Thomas (Author) , Hörner-Rieber, Juliane (Author) , Kappes, Jutta (Author) , Thomas, Michael (Author) , Heußel, Claus Peter (Author) , Steins, Martin (Author) , Kieser, Meinhard (Author) , Debus, Jürgen (Author) , Rieken, Stefan (Author)
Format:	Article (Journal)
Language:	English
Published:	16 July 2018
In:	Trials Year: 2018, Volume: 19, Pages: 1-8
ISSN:	1468-6694
DOI:	10.1186/s13063-018-2745-x
Online Access:	Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13063-018-2745-x Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-018-2745-x
Author Notes:	Denise Bernhardt, Adriane Hommertgen, Daniela Schmitt, Rami El Shafie, Angela Paul, Laila König, Johanna Mair-Walther, Johannes Krisam, Christina Klose, Thomas Welzel, Juliane Hörner-Rieber, Jutta Kappes, Michael Thomas, Claus Peter Heußel, Martin Steins, Meinhard Kieser, Jürgen Debus and Stefan Rieken