Whole-body MRI in patients with non-bacterial osteitis: radiological findings and correlation with clinical data
OBJECTIVES: To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent...
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
European radiology
Year: 2016, Jahrgang: 27, Heft: 6, Pages: 2391-2399 |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-016-4586-x |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00330-016-4586-x
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| Verfasserangaben: | A.P. Arnoldi, C.L. Schlett, H. Douis, L.L. Geyer, A.M. Voit, F. Bleisteiner, A.F. Jansson, S. Weckbach |
| Zusammenfassung: | OBJECTIVES: To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent clinical examination and WB-MRI in which STIR- and T1- weighted images were assessed for NBO-typical lesions. Parameters of interest for RINBO were: number of radiologically active lesions (RAL), size of the patients' maximum RAL presence of extramedullary and spinal involvement. Results were tested for statistical agreement of clinical and MR-based lesion detection. RINBO was tested for correlation with clinical activity. RESULTS: 62/95 clinically/radiologically active lesions were found in 30/33 patients. In 45 % of the cohort, more active lesions were detected by WB-MRI than by clinical examination. RINBO was a significant predictor for the presence of clinically active lesions. CONCLUSION: WB-MRI is a powerful diagnostic tool for patients with NBO which can reveal asymptomatic disease activity. With RINBO a standardized evaluation approach is proposed which helps assessing radiologic disease burden and predicts clinical disease activity. KEY POINTS: • Whole body MRI is a powerful diagnostic tool for patients with non-bacterial Osteitis. • Whole body MRI can reveal asymptomatic disease activity. • The radiologic index RINBO offers a standardized evaluation approach. |
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| Beschreibung: | First online: 23 September 2016 Gesehen am 08.08.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-016-4586-x |