Whole-body MRI in patients with non-bacterial osteitis: radiological findings and correlation with clinical data
OBJECTIVES: To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
European radiology
Year: 2016, Volume: 27, Issue: 6, Pages: 2391-2399 |
| ISSN: | 1432-1084 |
| DOI: | 10.1007/s00330-016-4586-x |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1007/s00330-016-4586-x |
| Author Notes: | A.P. Arnoldi, C.L. Schlett, H. Douis, L.L. Geyer, A.M. Voit, F. Bleisteiner, A.F. Jansson, S. Weckbach |
MARC
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| 245 | 1 | 0 | |a Whole-body MRI in patients with non-bacterial osteitis |b radiological findings and correlation with clinical data |c A.P. Arnoldi, C.L. Schlett, H. Douis, L.L. Geyer, A.M. Voit, F. Bleisteiner, A.F. Jansson, S. Weckbach |
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| 520 | |a OBJECTIVES: To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent clinical examination and WB-MRI in which STIR- and T1- weighted images were assessed for NBO-typical lesions. Parameters of interest for RINBO were: number of radiologically active lesions (RAL), size of the patients' maximum RAL presence of extramedullary and spinal involvement. Results were tested for statistical agreement of clinical and MR-based lesion detection. RINBO was tested for correlation with clinical activity. RESULTS: 62/95 clinically/radiologically active lesions were found in 30/33 patients. In 45 % of the cohort, more active lesions were detected by WB-MRI than by clinical examination. RINBO was a significant predictor for the presence of clinically active lesions. CONCLUSION: WB-MRI is a powerful diagnostic tool for patients with NBO which can reveal asymptomatic disease activity. With RINBO a standardized evaluation approach is proposed which helps assessing radiologic disease burden and predicts clinical disease activity. KEY POINTS: • Whole body MRI is a powerful diagnostic tool for patients with non-bacterial Osteitis. • Whole body MRI can reveal asymptomatic disease activity. • The radiologic index RINBO offers a standardized evaluation approach. | ||
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| 650 | 4 | |a Non-bacterial Osteitis | |
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