Epstein-Barr virus particles induce centrosome amplification and chromosomal instability

Infections with Epstein-Barr virus (EBV) are associated with cancer development, and EBV lytic replication (the process that generates virus progeny) is a strong risk factor for some cancer types. Here we report that EBV infection of B-lymphocytes (in vitro and in a mouse model) leads to an increase...

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Bibliographic Details

Main Authors:	Shumilov, Anatoliy (Author) , Tsai, Ming-Han (Author) , Bernhardt, Katharina (Author) , Delecluse, Susanne (Author) , Mizani, Tuba (Author) , Lin, Xiaochen (Author) , Jauch, Anna (Author) , Kopp-Schneider, Annette (Author) , Feederle, Regina (Author) , Hoffmann, Ingrid (Author) , Delecluse, Henri-Jacques (Author)
Format:	Article (Journal)
Language:	English
Published:	10 Feb 2017
In:	Nature Communications Year: 2017, Volume: 8
ISSN:	2041-1723
DOI:	10.1038/ncomms14257
Online Access:	Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/ncomms14257 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/ncomms14257
Author Notes:	Anatoliy Shumilov, Ming-Han Tsai, Yvonne T. Schlosser, Anne-Sophie Kratz, Katharina Bernhardt, Susanne Fink, Tuba Mizani, Xiaochen Lin, Anna Jauch, Josef Mautner, Annette Kopp-Schneider, Regina Feederle, Ingrid Hoffmann and Henri-Jacques Delecluse