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Smooth muscle proteins from Hirschsprung’s disease facilitates stem cell differentiation

Background and aims The transplantation of neural crest derived stem cells (NCSC’s) is a potent alternative for the treatment of Hirschsprung’s disease (HSCR). Cells to be transplanted should find an appropriate microenvironment to survive and differentiate. To investigate the quality of this microen...

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Bibliographic Details
Main Authors: Hagl, Cornelia Irene (Author) , Heumüller, Sabine (Author) , Wessel, Lucas (Author) , Schäfer, Karl Herbert (Author)
Format: Article (Journal)
Language:English
Published: 2012
In: Pediatric surgery international
Year: 2011, Volume: 28, Issue: 2, Pages: 135-142
ISSN:1437-9813
DOI:10.1007/s00383-011-3010-5
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s00383-011-3010-5
Verlag, Volltext: http://link.springer.com/10.1007/s00383-011-3010-5
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Author Notes:Cornelia Irene Hagl, Sabine Heumüller, Markus Klotz, Ulrike Subotic, Lucas Wessel, Karl-Herbert Schäfer
Description
Summary:Background and aims The transplantation of neural crest derived stem cells (NCSC’s) is a potent alternative for the treatment of Hirschsprung’s disease (HSCR). Cells to be transplanted should find an appropriate microenvironment to survive and differentiate. To investigate the quality of this microenvironment, effects of HSCR-smooth-muscleprotein extracts upon NCSC’s were studied in vitro.
Item Description:Published online: 3 November 2011
Gesehen am 09.08.2018
Physical Description:Online Resource
ISSN:1437-9813
DOI:10.1007/s00383-011-3010-5

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