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Risk factors of long-term postoperative renal function after partial nephrectomy in a solitary kidney

The effect of warm ischemia time (WIT) on longterm renal function after partial nephrectomy remains controversial. In this retrospectively cohort study, 75 solitary kidney patients were included and the effects of warm ischemia time, preoperative renal function and resected normal parenchyma volume...

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Main Authors: Zhu, Jie (Author) , Kuru, Timur Hasan (Author) , Hatiboglu, Gencay (Author) , Popeneciu, Valentin (Author) , Schoenberg, Gita (Author) , Simpfendörfer, Tobias (Author) , Zeier, Martin (Author) , Hohenfellner, Markus (Author) , Pahernik, Sascha (Author)
Format: Article (Journal)
Language:English
Published: 29.12.2017
In: Open life sciences
Year: 2017, Volume: 12, Issue: 1, Pages: 481-488
ISSN:2391-5412
DOI:10.1515/biol-2017-0057
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1515/biol-2017-0057
Verlag, kostenfrei, Volltext: https://www.degruyterbrill.com/view/j/biol.2017.12.issue-1/biol-2017-0057/biol-2017-0057.xml
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Author Notes:Jie Zhu, Timur Kuru, Yingqi Wei, Gencay Hatiboglu, Valentin Popeneciu, Gita Schöenberg, Tobias Simpfendörfer, Martin Zeier, Ma Xin, Xu Zhang, Markus Hohenfellner, Sascha Pahernik
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Summary:The effect of warm ischemia time (WIT) on longterm renal function after partial nephrectomy remains controversial. In this retrospectively cohort study, 75 solitary kidney patients were included and the effects of warm ischemia time, preoperative renal function and resected normal parenchyma volume on long-term renal function were evaluated. Multivariable analysis showed that the preoperative renal function baseline was significantly associated with renal function 12 months postoperation (P=0.01), adjusting for age and comorbidities factors. Meanwhile, perioperative acute renal failure (ARF) events significantly affected postoperative renal function at postoperative time points of 12 months (P=0.001) and 60 months (P=0.03), as well as renal function change at postoperative 12 months (P<0.01). Warm ischemia time and resected normal parenchyma volume were not risk factors for long-term postoperative renal function, while the latter was significantly associated with renal function change (P=0.03 at 12 months, P<0.01 at 36 and 60 months).
Item Description:Online erschienen: 29.12.2017
Gesehen am 10.08.2018
Physical Description:Online Resource
ISSN:2391-5412
DOI:10.1515/biol-2017-0057

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