3-T high-b-value diffusion-weighted MR imaging of hyperacute ischemic stroke in the vertebrobasilar territory = Imagerie de diffusion en IRM 3T à b élevé dans l’accident ischémique hyperaigu du territoire vertébobasilaire
Background and purpose: Diffusion-weighted imaging (DWI) is the key method for diagnosing acute ischemic stroke. Applied b values in stroke diffusion studies are usually in the range of 800–1500 s/mm2, but progress in magnetic resonance (MR) technology now permits higher b values. However, it is unc...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English French |
| Published: |
2012
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| In: |
Journal of neuroradiology
Year: 2011, Volume: 39, Issue: 4, Pages: 243-253 |
| ISSN: | 1773-0406 |
| DOI: | 10.1016/j.neurad.2011.09.005 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.neurad.2011.09.005 Verlag, Volltext: https://www.sciencedirect.com/science/article/pii/S015098611100112X 
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| Author Notes: | Michael Lettau, Mona Laible |
| Summary: | Background and purpose: Diffusion-weighted imaging (DWI) is the key method for diagnosing acute ischemic stroke. Applied b values in stroke diffusion studies are usually in the range of 800–1500 s/mm2, but progress in magnetic resonance (MR) technology now permits higher b values. However, it is uncertain whether high-b-value DW sequences improve the detection of acute and hyperacute ischemic lesions. The aim of this study is to explore the sensitivity of high b values vs standard b values at 3 T in hyperacute stroke in the vertebrobasilar territory. Material and methods: 3-T DWI was performed in referred patients with a clinical diagnosis of hyperacute (< 6 h from onset) cerebral infarction using conventional MR sequences as well as DW sequences. Examinations included the usual DW sequence (b = 1000 s/mm2) and two high-b-value DW sequences (b = 3000 s/mm2 and b = 5000 s/mm2). Patients with hyperacute stroke in the posterior circulation were included if MR imaging, including the usual DW sequence, was normal or if the diagnosis was uncertain.Results: In all six studied patients, ischemic lesions were better visualized with high-b-value DWI compared with the usual DWI. On increasing the b value, DW images appeared to be noisier while white-matter tracts became progressively hyperintense. Conclusion: At 3 T, high-b-value DW sequences may be helpful for diagnosing hyperacute infarctions in the vertebrobasilar territory, but further studies are needed to confirm this hypothesis. |
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| Item Description: | Available online 16 December 2011 Gesehen am 23.08.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1773-0406 |
| DOI: | 10.1016/j.neurad.2011.09.005 |