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TARGIT-E(lderly): prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer

Patients ≥ 70 years with small, low-risk breast cancer who are operated but not irradiated how local relapse rates around 4% after 4 years. With adjuvant whole breast radiotherapy (WBRT) the local relapse rate drops to 1% after 4 years under Tamoxifen. It has been demonstrated that the efficacy of r...

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Main Authors: Neumaier, Christian (Author) , Sperk, Elena (Author) , Welzel, Grit (Author) , Abo-Madyan, Yasser (Author) , Kraus-Tiefenbacher, Uta (Author) , Keller, Anke (Author) , Gerhardt, Axel (Author) , Sütterlin, Marc (Author) , Wenz, Frederik (Author)
Format: Article (Journal)
Language:English
Published: 8 May 2012
In: BMC cancer
Year: 2012, Volume: 12
ISSN:1471-2407
DOI:10.1186/1471-2407-12-171
Online Access:Resolving-System, kostenfrei, Volltext: http://dx.doi.org/10.1186/1471-2407-12-171
Verlag, kostenfrei, Volltext: https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-12-171
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Author Notes:Christian Neumaier, Sperk Elena, Welzel Grit, Abo-Madyan Yasser, Kraus-Tiefenbacher Uta, Keller Anke, Gerhardt Axel, Sütterlin Marc and Wenz Frederik
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Summary:Patients ≥ 70 years with small, low-risk breast cancer who are operated but not irradiated how local relapse rates around 4% after 4 years. With adjuvant whole breast radiotherapy (WBRT) the local relapse rate drops to 1% after 4 years under Tamoxifen. It has been demonstrated that the efficacy of radiotherapy of the tumor bed only in a selected group can be non-inferior to WBRT.
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Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/1471-2407-12-171

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