Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial
Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess whether combining the treatments would be more effective than hormonal therapy alone.
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2017
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| In: |
The lancet
Year: 2016, Jahrgang: 16, Heft: 1, Pages: 33-42 |
| ISSN: | 1474-4465 |
| DOI: | 10.1016/S1474-4422(16)30294-0 |
| Online-Zugang: | Resolving-System, Volltext: http://dx.doi.org/10.1016/S1474-4422(16)30294-0 Verlag, Volltext: https://www.sciencedirect.com/science/article/pii/S1474442216302940 
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| Verfasserangaben: | Finbar J.K. O’Callaghan, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew A. Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, John P. Osborne |
| Zusammenfassung: | Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess whether combining the treatments would be more effective than hormonal therapy alone. |
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| Beschreibung: | Published online November 9, 2016 Gesehen am 04.09.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1474-4465 |
| DOI: | 10.1016/S1474-4422(16)30294-0 |