Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial
Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess whether combining the treatments would be more effective than hormonal therapy alone.
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
The lancet
Year: 2016, Volume: 16, Issue: 1, Pages: 33-42 |
| ISSN: | 1474-4465 |
| DOI: | 10.1016/S1474-4422(16)30294-0 |
| Online Access: | Resolving-System, Volltext: http://dx.doi.org/10.1016/S1474-4422(16)30294-0 Verlag, Volltext: https://www.sciencedirect.com/science/article/pii/S1474442216302940 
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| Author Notes: | Finbar J.K. O’Callaghan, Stuart W. Edwards, Fabienne Dietrich Alber, Eleanor Hancock, Anthony L. Johnson, Colin R. Kennedy, Marcus Likeman, Andrew L. Lux, Mark Mackay, Andrew A. Mallick, Richard W. Newton, Melinda Nolan, Ronit Pressler, Dietz Rating, Bernhard Schmitt, Christopher M. Verity, John P. Osborne |
| Summary: | Infantile spasms constitutes a severe infantile epilepsy syndrome that is difficult to treat and has a high morbidity. Hormonal therapies or vigabatrin are the most commonly used treatments. We aimed to assess whether combining the treatments would be more effective than hormonal therapy alone. |
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| Item Description: | Published online November 9, 2016 Gesehen am 04.09.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1474-4465 |
| DOI: | 10.1016/S1474-4422(16)30294-0 |