Non-coding RNA in hepatocellular carcinoma: mechanisms, biomarkers and therapeutic targets

The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their p...

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Bibliographic Details
Main Authors: Klingenberg, Marcel (Author) , Diederichs, Sven (Author)
Format: Article (Journal)
Language:English
Published: 2017 Apr 22
In: Journal of hepatology
Year: 2017, Volume: 67, Issue: 3, Pages: 603-618
ISSN:1600-0641
DOI:10.1016/j.jhep.2017.04.009
Online Access:Verlag, Volltext: https://doi.org/10.1016/j.jhep.2017.04.009
Verlag, Volltext: https://www.journal-of-hepatology.eu/article/S0168-8278(17)30250-7/abstract
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Author Notes:Marcel Klingenberg, Akiko Matsuda, Sven Diederichs, Tushar Patel
Description
Summary:The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their potential use for the detection and treatment of liver cancer.
Item Description:Gesehen am 14.09.2018
Physical Description:Online Resource
ISSN:1600-0641
DOI:10.1016/j.jhep.2017.04.009