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3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 differen...

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Bibliographic Details
Main Authors: Jürchott, Alexander (Author) , Saleem, Muhammad Abdullah (Author) , Hilgenfeld, Tim (Author) , Freudlsperger, Christian (Author) , Zingler, Sebastian (Author) , Lux, Christopher J. (Author) , Bendszus, Martin (Author) , Heiland, Sabine (Author)
Format: Article (Journal)
Language:English
Published: 29 August 2018
In: Scientific reports
Year: 2018, Volume: 8
ISSN:2045-2322
DOI:10.1038/s41598-018-31384-8
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/s41598-018-31384-8
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41598-018-31384-8
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Author Notes:Alexander Juerchott, Muhammad Abdullah Saleem, Tim Hilgenfeld, Christian Freudlsperger, Sebastian Zingler, Christopher J. Lux, Martin Bendszus & Sabine Heiland
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Summary:The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p  0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and reproducible 3D cephalometric analysis can be performed without exposure to ionizing radiation using MRI.
Item Description:Gesehen am 20.09.2018
Physical Description:Online Resource
ISSN:2045-2322
DOI:10.1038/s41598-018-31384-8

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