DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications

We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microo...

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Bibliographische Detailangaben
Hauptverfasser: Boles, Erica Ann (VerfasserIn) , Geyer, Florian Ludwig (VerfasserIn) , Nedashkivska, Victoria (VerfasserIn) , Levkin, Pavel (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 Oct 2012
In: Lab on a chip
Year: 2012, Jahrgang: 12, Heft: 24, Pages: 5218-5224
ISSN:1473-0189
DOI:10.1039/C2LC40921F
Online-Zugang:Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1039/C2LC40921F
Verlag, Pay-per-use, Volltext: https://pubs.rsc.org/en/content/articlelanding/2012/lc/c2lc40921f
Volltext
Verfasserangaben:Erica Ueda, Florian L. Geyer, Victoria Nedashkivska and Pavel A. Levkin
Beschreibung
Zusammenfassung:We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments.
Beschreibung:Gesehen am 24.09.2018
Beschreibung:Online Resource
ISSN:1473-0189
DOI:10.1039/C2LC40921F