DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications
We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microo...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 Oct 2012
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| In: |
Lab on a chip
Year: 2012, Jahrgang: 12, Heft: 24, Pages: 5218-5224 |
| ISSN: | 1473-0189 |
| DOI: | 10.1039/C2LC40921F |
| Online-Zugang: | Verlag, Pay-per-use, Volltext: http://dx.doi.org/10.1039/C2LC40921F Verlag, Pay-per-use, Volltext: https://pubs.rsc.org/en/content/articlelanding/2012/lc/c2lc40921f |
| Verfasserangaben: | Erica Ueda, Florian L. Geyer, Victoria Nedashkivska and Pavel A. Levkin |
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| 520 | |a We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments. | ||
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