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Osseointegrative effect of rhBMP-2 covalently bound on a titan-plasma-spray-surface after modification with chromosulfuric acid in a large animal bone gap-healing model with the Göttingen minipig

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Bone morphogenetic proteins play an important role as osseointegrative factors. It is used widely in orthopedic research and surgery to enhance the osseointegrative potential of implants, e.g., in spinal fusion or alveolar socket augmentation. The aim of the present study was to investigate the bene...

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Bibliographic Details
Main Authors: Lingner, Manuel (Author) , Lehmann, Lars (Author) , Mauermann, Eckhard (Author) , Obertacke, Udo (Author) , Schwarz, Markus (Author)
Format: Article (Journal)
Language:English
Published: 30 August 2018
In: Journal of orthopaedic surgery and research
Year: 2018, Volume: 13
ISSN:1749-799X
DOI:10.1186/s13018-018-0915-x
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13018-018-0915-x
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13018-018-0915-x
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Author Notes:Manuel Lingner, Roland Seidling, Lars Johannes Lehmann, Eckhard Mauermann, Udo Obertacke and Markus Ludwig Rupert Schwarz
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Summary:Bone morphogenetic proteins play an important role as osseointegrative factors. It is used widely in orthopedic research and surgery to enhance the osseointegrative potential of implants, e.g., in spinal fusion or alveolar socket augmentation. The aim of the present study was to investigate the benefit of rhBMP-2 on a titan plasma spray (TPS) layer after a special modification with chromosulfuric acid (CSA) at different postoperative times, regarding osseoconduction and osseoinduction.
Item Description:Gesehen am 25.09.2018
Physical Description:Online Resource
ISSN:1749-799X
DOI:10.1186/s13018-018-0915-x

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