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Opposite effects of tissue inhibitor of metalloproteinases-1 (TIMP-1) over-expression and knockdown on colorectal liver metastases

Tissue inhibitors of metalloproteinases (TIMPs) and the corresponding metalloproteinases are integral parts of the protease network and have been shown to be involved in cancer development and metastasis. Paradoxically, for TIMP-1, tumor promoting as well as tumor inhibitory effects have been observ...

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Bibliographic Details
Main Authors: Bandapalli, Obul Reddy (Author) , Paul, Eva (Author) , Schirmacher, Peter (Author) , Brand, Karsten (Author)
Format: Article (Journal)
Language:English
Published: 9 January 2012
In: BMC Research Notes
Year: 2012, Volume: 5
ISSN:1756-0500
DOI:10.1186/1756-0500-5-14
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1756-0500-5-14
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1756-0500-5-14
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Author Notes:Obul R. Bandapalli, Eva Paul, Peter Schirmacher and Karsten Brand
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Summary:Tissue inhibitors of metalloproteinases (TIMPs) and the corresponding metalloproteinases are integral parts of the protease network and have been shown to be involved in cancer development and metastasis. Paradoxically, for TIMP-1, tumor promoting as well as tumor inhibitory effects have been observed.
Item Description:Gesehen am 26.09.2018
Physical Description:Online Resource
ISSN:1756-0500
DOI:10.1186/1756-0500-5-14

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