Hepatitis B virus infection of HepaRG cells, HepaRG-hNTCP cells, and primary human hepatocytes

Here, we describe in detail how to technically perform HBV infection in vitro with these cells. The methods can be used to explore the mechanism of HBV infection and to build an antiviral screening platform suitable for evaluation of drug efficacy in cells that are metabolically close to primary hum...

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Bibliographic Details
Main Authors: Ni, Yi (Author) , Urban, Stephan (Author)
Format: Chapter/Article
Language:English
Published: 2017
In: Hepatitis B Virus
Year: 2016, Pages: 15-25
DOI:10.1007/978-1-4939-6700-1_2
Online Access:Resolving-System, Volltext: http://dx.doi.org/10.1007/978-1-4939-6700-1_2
Verlag, Volltext: https://link.springer.com/protocol/10.1007/978-1-4939-6700-1_2
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Author Notes:Yi Ni, Stephan Urban
Description
Summary:Here, we describe in detail how to technically perform HBV infection in vitro with these cells. The methods can be used to explore the mechanism of HBV infection and to build an antiviral screening platform suitable for evaluation of drug efficacy in cells that are metabolically close to primary human hepatocytes.
Item Description:First online: 15 December 2016
Gesehen am 27.09.2018
Physical Description:Online Resource
ISBN:9781493967001
DOI:10.1007/978-1-4939-6700-1_2