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Thromboembolic stroke in C57BL/6 mice monitored by 9.4 T MRI using a 1H cryo probe

A new thromboembolic animal model showed beneficial effects of t-PA with an infarct volume reduction of 36.8% in swiss mice. Because knock-out animal experiments for stroke frequently used C57BL76 mice we evaluated t-PA effects in this mouse strain and measured infarct volume and vascular recanalisa...

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Hauptverfasser: Langhauser, Friederike (VerfasserIn) , Grudzenski-Theis, Saskia (VerfasserIn) , Lemke, Andreas (VerfasserIn) , Alonso, Angelika (VerfasserIn) , Schad, Lothar R. (VerfasserIn) , Hennerici, Michael G. (VerfasserIn) , Meairs, Stephen (VerfasserIn) , Fatar, Marc (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 September 2012
In: Experimental & translational stroke medicine
Year: 2012, Jahrgang: 4
ISSN:2040-7378
DOI:10.1186/2040-7378-4-18
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/2040-7378-4-18
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/2040-7378-4-18
Volltext
Verfasserangaben:Friederike L. Langhauser, Patrick M. Heiler, Saskia Grudzenski, Andreas Lemke, Angelika Alonso, Lothar R. Schad, Michael G. Hennerici, Stephen Meairs and Marc Fatar
Beschreibung
Zusammenfassung:A new thromboembolic animal model showed beneficial effects of t-PA with an infarct volume reduction of 36.8% in swiss mice. Because knock-out animal experiments for stroke frequently used C57BL76 mice we evaluated t-PA effects in this mouse strain and measured infarct volume and vascular recanalisation in-vivo by using high-field 9.4 T MRI and a 1H surface cryo coil.
Beschreibung:Gesehen am 01.10.2018
Beschreibung:Online Resource
ISSN:2040-7378
DOI:10.1186/2040-7378-4-18

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