Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients
Burn patients are prone to infections which often necessitate broad antibiotic coverage. Vancomycin is a common antibiotic after burn injury and is administered alone (V), or in combination with imipenem-cilastin (V/IC) or piperacillin-tazobactam (V/PT). Sparse reports indicate that the combination...
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| Main Author: | |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
20 December 2017
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| In: |
Critical care
Year: 2017, Volume: 21 |
| ISSN: | 1466-609X |
| DOI: | 10.1186/s13054-017-1899-3 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13054-017-1899-3 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13054-017-1899-3 
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| Author Notes: | Gabriel Hundeshagen, David N. Herndon, Karel D. Capek, Ludwik K. Branski, Charles D. Voigt, Elizabeth A. Killion, Janos Cambiaso-Daniel, Michaela Sljivich, Andrew De Crescenzo, Ronald P. Mlcak, Michael P. Kinsky, Celeste C. Finnerty, William B. Norbury |
| Summary: | Burn patients are prone to infections which often necessitate broad antibiotic coverage. Vancomycin is a common antibiotic after burn injury and is administered alone (V), or in combination with imipenem-cilastin (V/IC) or piperacillin-tazobactam (V/PT). Sparse reports indicate that the combination V/PT is associated with increased renal dysfunction. The purpose of this study was to evaluate the short-term impact of the three antibiotic administration types on renal dysfunction. |
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| Item Description: | Gesehen am 04.10.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1466-609X |
| DOI: | 10.1186/s13054-017-1899-3 |