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Soziale Umweltrisikofaktoren und psychische Erkrankungen: Einblicke in zugrunde liegende Gehirnmechanismen am Beispiel der Urbanizität = Social environmental risk factors and mental disorders

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Summary: The importance of social environmental factors for mental disorders is well known; nonetheless explanations of the underlying associations are still incomplete. For example this holds true for the schizophrenia risk factor urban upbringing (early urbanicity), which puzzled researchers for a...

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Bibliographic Details
Main Authors: Haller, Leila (Author) , Meyer-Lindenberg, Andreas (Author)
Format: Article (Journal)
Language:German
English
Published: 25. Oktober 2012
In: Der Nervenarzt
Year: 2012, Volume: 83, Issue: 11, Pages: 1403-1409
ISSN:1433-0407
DOI:10.1007/s00115-012-3664-9
Online Access:Verlag, Volltext: http://dx.doi.org/10.1007/s00115-012-3664-9
Verlag, Volltext: https://doi.org/10.1007/s00115-012-3664-9
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Author Notes:L. Haddad, A. Meyer-Lindenberg
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Summary:Summary: The importance of social environmental factors for mental disorders is well known; nonetheless explanations of the underlying associations are still incomplete. For example this holds true for the schizophrenia risk factor urban upbringing (early urbanicity), which puzzled researchers for a long time. This article reports on recently identified neural correlates of this factor in the context of social stress processing. Drawing on this example, it is demonstrated how the identification of such correlates can contribute to the etiological understanding of mental disorders. While including genetic risk mechanisms and gene-environment interactions, a theoretical model is specified that postulates changes in the perigenual anterior cingulate cortex (pACC) and a heightened sensitivity towards social stressors as the relevant link between risk of schizophrenia and early urbanicity.
Item Description:Zusammenfassung in deutscher und englischer Sprache, Artikel in deutscher Sprache
Gesehen am 09.10.2018
Physical Description:Online Resource
ISSN:1433-0407
DOI:10.1007/s00115-012-3664-9

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