A novel way to measure and predict development: a heuristic approach to facilitate the early detection of neurodevelopmental disorders
Purpose of ReviewSubstantial research exists focusing on the various aspects and domains of early human development. However, there is a clear blind spot in early postnatal development when dealing with neurodevelopmental disorders, especially those that manifest themselves clinically only in late i...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
8 April 2017
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| In: |
Current neurology and neuroscience reports
Year: 2017, Volume: 17, Issue: 5 |
| ISSN: | 1534-6293 |
| DOI: | 10.1007/s11910-017-0748-8 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1007/s11910-017-0748-8 Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s11910-017-0748-8 
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| Author Notes: | Peter B. Marschik, Florian B. Pokorny, Robert Peharz, Dajie Zhang, Jonathan O’Muircheartaigh, Herbert Roeyers, Sven Bölte, Alicia J. Spittle, Berndt Urlesberger, Björn Schuller, Luise Poustka, Sally Ozonoff, Franz Pernkopf, Thomas Pock, Kristiina Tammimies, Christian Enzinger, Magdalena Krieber, Iris Tomantschger, Katrin D. Bartl-Pokorny, Jeff Sigafoos, Laura Roche, Gianluca Esposito, Markus Gugatschka, Karin Nielsen-Saines, Christa Einspieler, Walter E. Kaufmann, the BEE-PRI Study Group |
| Summary: | Purpose of ReviewSubstantial research exists focusing on the various aspects and domains of early human development. However, there is a clear blind spot in early postnatal development when dealing with neurodevelopmental disorders, especially those that manifest themselves clinically only in late infancy or even in childhood.Recent FindingsThis early developmental period may represent an important timeframe to study these disorders but has historically received far less research attention. We believe that only a comprehensive interdisciplinary approach will enable us to detect and delineate specific parameters for specific neurodevelopmental disorders at a very early age to improve early detection/diagnosis, enable prospective studies and eventually facilitate randomised trials of early intervention.SummaryIn this article, we propose a dynamic framework for characterising neurofunctional biomarkers associated with specific disorders in the development of infants and children. We have named this automated detection ‘Fingerprint Model’, suggesting one possible approach to accurately and early identify neurodevelopmental disorders. |
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| Item Description: | Gesehen am 17.10.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1534-6293 |
| DOI: | 10.1007/s11910-017-0748-8 |