Aggregation and Interaction of cationic nanoparticles on bacterial surfaces

Cationic monolayer-protected gold nanoparticles (AuNPs) with sizes of 6 or 2 nm interact with the cell membranes of Escherichia coli (Gram−) and Bacillus subtilis (Gram+), resulting in the formation of strikingly distinct AuNP surface aggregation patterns or lysis depending upon the size of the AuNP...

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Bibliographic Details
Main Authors: Hayden, Steven C. (Author) , Bunz, Uwe H. F. (Author)
Format: Article (Journal)
Language:English
Published: 25 April 2012
In: Journal of the American Chemical Society
Year: 2012, Volume: 134, Issue: 16, Pages: 6920-6923
ISSN:1520-5126
DOI:10.1021/ja301167y
Online Access:Verlag, Volltext: http://dx.doi.org/10.1021/ja301167y
Verlag, Volltext: http://pubs.acs.org/doi/10.1021/ja301167y
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Author Notes:Steven C. Hayden, Gengxiang Zhao, Krishnendu Saha, Ronnie L. Phillips, Xiaoning Li, Oscar R. Miranda, Vincent M. Rotello, Mostafa A. El-Sayed, Ingeborg Schmidt-Krey, and Uwe H.F. Bunz
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Summary:Cationic monolayer-protected gold nanoparticles (AuNPs) with sizes of 6 or 2 nm interact with the cell membranes of Escherichia coli (Gram−) and Bacillus subtilis (Gram+), resulting in the formation of strikingly distinct AuNP surface aggregation patterns or lysis depending upon the size of the AuNPs. The aggregation phenomena were investigated by transmission electron microscopy and UV−vis spectroscopy. Upon proteolytic treatment of the bacteria, the distinct aggregation patterns disappeared.
Item Description:Published online17 April 2012
Gesehen am 18.10.2018
Physical Description:Online Resource
ISSN:1520-5126
DOI:10.1021/ja301167y