O-GlcNAcylation of a circadian clock protein: dPER taking its sweet time

In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the s...

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Bibliographic Details
Main Authors: Diernfellner, Axel (Author) , Brunner, Michael (Author)
Format: Article (Journal)
Language:English
Published: March 1, 2012
In: Genes & development
Year: 2012, Volume: 26, Issue: 5, Pages: 415-416
ISSN:1549-5477
DOI:10.1101/gad.188524.112
Online Access:Verlag, Volltext: http://dx.doi.org/10.1101/gad.188524.112
Verlag, Volltext: http://genesdev.cshlp.org/content/26/5/415
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Author Notes:Axel C. R. Diernfellner and Michael Brunner
Description
Summary:In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the stability and nuclear translocation of dPER.
Item Description:Published in advanced: February 10, 2012
Gesehen am 22.10.2018
Physical Description:Online Resource
ISSN:1549-5477
DOI:10.1101/gad.188524.112