O-GlcNAcylation of a circadian clock protein: dPER taking its sweet time
In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the s...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 1, 2012
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| In: |
Genes & development
Year: 2012, Jahrgang: 26, Heft: 5, Pages: 415-416 |
| ISSN: | 1549-5477 |
| DOI: | 10.1101/gad.188524.112 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1101/gad.188524.112 Verlag, Volltext: http://genesdev.cshlp.org/content/26/5/415 |
| Verfasserangaben: | Axel C. R. Diernfellner and Michael Brunner |
| Zusammenfassung: | In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the stability and nuclear translocation of dPER. |
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| Beschreibung: | Published in advanced: February 10, 2012 Gesehen am 22.10.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1549-5477 |
| DOI: | 10.1101/gad.188524.112 |