O-GlcNAcylation of a circadian clock protein: dPER taking its sweet time

In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the s...

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Hauptverfasser: Diernfellner, Axel (VerfasserIn) , Brunner, Michael (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 1, 2012
In: Genes & development
Year: 2012, Jahrgang: 26, Heft: 5, Pages: 415-416
ISSN:1549-5477
DOI:10.1101/gad.188524.112
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1101/gad.188524.112
Verlag, Volltext: http://genesdev.cshlp.org/content/26/5/415
Volltext
Verfasserangaben:Axel C. R. Diernfellner and Michael Brunner

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520 |a In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the stability and nuclear translocation of dPER. 
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650 4 |a nuclear entry 
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787 0 8 |i Kommentar zu  |a Kim, E. Y. et al  |t A role for O-GlcNAcylation in setting circadian clock speed  |d 2012  |g 26(2012,5), Seite 490-502 
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