Heme oxygenase 1-generated carbon monoxide and biliverdin attenuate the course of experimental necrotizing pancreatitis

The cytoprotective enzyme heme oxygenase 1 (HO-1) is highly up-regulated in acute pancreatitis (AP). In this study, we tested its metabolites as potential therapeutic agents for AP in rats.

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Bibliographic Details
Main Authors: Nuhn, Philipp (Author) , Bergmann, Frank (Author) , Fischer, Lars (Author) , Giese, Nathalia (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Pancreas
Year: 2013, Volume: 42, Issue: 2, Pages: 265-271
ISSN:1536-4828
DOI:10.1097/MPA.0b013e318264cc8b
Online Access:Resolving-System, Volltext: http://dx.doi.org/10.1097/MPA.0b013e318264cc8b
Verlag, Volltext: https://journals.lww.com/pancreasjournal/Abstract/2013/03000/Heme_Oxygenase_1_Generated_Carbon_Monoxide_and.13.aspx
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Author Notes:Philipp Nuhn, Tomas Mitkus, Güralp O. Ceyhan, Beat M. Künzli, Frank Bergmann, Lars Fischer, Nathalia Giese, Helmut Friess, and Pascal O. Berberat
Description
Summary:The cytoprotective enzyme heme oxygenase 1 (HO-1) is highly up-regulated in acute pancreatitis (AP). In this study, we tested its metabolites as potential therapeutic agents for AP in rats.
Item Description:Gesehen am 29.10.2018
Physical Description:Online Resource
ISSN:1536-4828
DOI:10.1097/MPA.0b013e318264cc8b