Buchumschlag

M3: an integrative framework for structure determination of molecular machines

We present a broadly applicable, user-friendly protocol that incorporates sparse and hybrid experimental data to calculate quasi-atomic-resolution structures of molecular machines. The protocol uses the HADDOCK framework, accounts for extensive structural rearrangements both at the domain and atomic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Karaca, Ezgi (VerfasserIn) , Bonvin, Alexandre M. J. J. (VerfasserIn) , Carlomagno, Teresa (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 August 2017
In: Nature methods
Year: 2017, Jahrgang: 14, Heft: 9, Pages: 897-902
ISSN:1548-7105
DOI:10.1038/nmeth.4392
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1038/nmeth.4392
Verlag, Volltext: https://www.nature.com/articles/nmeth.4392
Volltext
Verfasserangaben:Ezgi Karaca, João P.G.L.M. Rodrigues, Andrea Graziadei, Alexandre M.J.J. Bonvin, Teresa Carlomagno
Beschreibung
Zusammenfassung:We present a broadly applicable, user-friendly protocol that incorporates sparse and hybrid experimental data to calculate quasi-atomic-resolution structures of molecular machines. The protocol uses the HADDOCK framework, accounts for extensive structural rearrangements both at the domain and atomic levels and accepts input from all structural and biochemical experiments whose data can be translated into interatomic distances and/or molecular shapes.
Beschreibung:Gesehen am 09.11.2018
Beschreibung:Online Resource
ISSN:1548-7105
DOI:10.1038/nmeth.4392

Ähnliche Einträge