Siglec-1 Is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides
The novel dendritic cell receptor Siglec-1 binds sialyllactose moieties on HIV-1 membrane gangliosides, thereby enhancing HIV-1 transinfection.
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
December 18, 2012
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| In: |
PLoS biology
Year: 2012, Volume: 10, Issue: 12 |
| ISSN: | 1545-7885 |
| DOI: | 10.1371/journal.pbio.1001448 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1371/journal.pbio.1001448 Verlag, kostenfrei, Volltext: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001448 |
| Author Notes: | Nuria Izquierdo-Useros, Maier Lorizate, Maria C. Puertas, Maria T. Rodriguez-Plata, Nadine Zangger, Elina Erikson, Maria Pino, Itziar Erkizia, Bärbel Glass, Bonaventura Clotet, Oliver T. Keppler, Amalio Telenti, Hans-Georg Kräusslich, Javier Martinez-Picado |
| Summary: | The novel dendritic cell receptor Siglec-1 binds sialyllactose moieties on HIV-1 membrane gangliosides, thereby enhancing HIV-1 transinfection. |
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| Item Description: | Gesehen am 21.11.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1545-7885 |
| DOI: | 10.1371/journal.pbio.1001448 |