Hypothesis testing in Bayesian network meta-analysis

Network meta-analysis is an extension of the classical pairwise meta-analysis and allows to compare multiple interventions based on both head-to-head comparisons within trials and indirect comparisons across trials. Bayesian or frequentist models are applied to obtain effect estimates with credible...

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Hauptverfasser: Uhlmann, Lorenz (VerfasserIn) , Jensen, Katrin (VerfasserIn) , Kieser, Meinhard (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 November 2018
In: BMC medical research methodology
Year: 2018, Jahrgang: 18
ISSN:1471-2288
DOI:10.1186/s12874-018-0574-y
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s12874-018-0574-y
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12874-018-0574-y
Volltext
Verfasserangaben:Lorenz Uhlmann, Katrin Jensen and Meinhard Kieser
Beschreibung
Zusammenfassung:Network meta-analysis is an extension of the classical pairwise meta-analysis and allows to compare multiple interventions based on both head-to-head comparisons within trials and indirect comparisons across trials. Bayesian or frequentist models are applied to obtain effect estimates with credible or confidence intervals. Furthermore, p-values or similar measures may be helpful for the comparison of the included arms but related methods are not yet addressed in the literature. In this article, we discuss how hypothesis testing can be done in a Bayesian network meta-analysis.
Beschreibung:Gesehen am 23.11.2018
Beschreibung:Online Resource
ISSN:1471-2288
DOI:10.1186/s12874-018-0574-y