Total ankle replacement in patients with von Willebrand disease: mid-term results of 18 procedures
von Willebrand disease (VWD) is a recognized cause of secondary ankle osteoarthritis (OA). Few studies have examined orthopaedic complications and outcomes in VWD patients treated for end-stage ankle OA with total ankle replacement (TAR). To determine the clinical presentation, intraoperative and po...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 February 2015
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| In: |
Haemophilia
Year: 2015, Volume: 21, Issue: 5, Pages: e389-e401 |
| ISSN: | 1365-2516 |
| DOI: | 10.1111/hae.12561 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1111/hae.12561 Verlag, Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1111/hae.12561 
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| Author Notes: | K. Barg, M. Wiewiorski, A.E. Anderson, S.W. Schneider, M.D. Wimmer, D.C. Wirtz, V. Valderrabano, A. Barg and G. Pagenstert |
| Summary: | von Willebrand disease (VWD) is a recognized cause of secondary ankle osteoarthritis (OA). Few studies have examined orthopaedic complications and outcomes in VWD patients treated for end-stage ankle OA with total ankle replacement (TAR). To determine the clinical presentation, intraoperative and postoperative complications and evaluate the mid-term outcome in VWD patients treated with TAR. Eighteen patients with VWD with mean age 47.3 years (range = 34.0-68.7) were treated for end-stage ankle OA with TAR. The mean duration of follow-up was 7.5 years (range = 2.9-13.2). Intraoperative and perioperative complications were recorded. Component stability was assessed with weight-bearing radiographs. Clinical evaluation included range of motion (ROM) tests using a goniometer and under fluoroscopy using a lateral view. Clinical outcomes were analysed by a visual analogue scale, the American Orthopaedic Foot and Ankle Society hindfoot score and Short Form (36) Health Survey (SF-36) health survey. One patient sustained an intraoperative medial malleolar fracture. In two patients delayed wound healing was observed. Two secondary major surgeries were performed. Pain level decreased from 8.2 ± 0.9 (range = 7-10) preoperatively to 1.1 ± 1.2 (range = 0-4) postoperatively. Significant functional improvement including ROM was observed. All categories of SF-36 score showed significant improvement in quality of life. Mid-term results of TAR in patients with VWD are encouraging. The total rate of intraoperative and postoperative complications was 33.3%. However, longer term outcomes are necessary to fully understand the clinical benefit of TAR in patients with VWD. |
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| Item Description: | Gesehen am 26.11.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1365-2516 |
| DOI: | 10.1111/hae.12561 |