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Prostate cancer molecular imaging standardized evaluation (PROMISE): proposed miTNM classification for the interpretation of PSMA-ligand PET/CT

Prostate-specific membrane antigen (PSMA)-ligand PET imaging provides unprecedented accuracy for whole-body staging of prostate cancer. As PSMA-ligand PET/CT is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. We propo...

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Bibliographic Details
Main Authors: Eiber, Matthias (Author) , Giesel, Frederik L. (Author)
Format: Article (Journal)
Language:English
Published: March 1, 2018
In: Journal of nuclear medicine
Year: 2018, Volume: 59, Issue: 3, Pages: 469-478
ISSN:2159-662X
DOI:10.2967/jnumed.117.198119
Online Access:Verlag, Volltext: http://dx.doi.org/10.2967/jnumed.117.198119
Verlag, Volltext: http://jnm.snmjournals.org/content/59/3/469
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Author Notes:Matthias Eiber, Ken Herrmann, Jeremie Calais, Boris Hadaschik, Frederik L. Giesel, Markus Hartenbach, Thomas Hope, Robert Reiter, Tobias Maurer, Wolfgang A. Weber, and Wolfgang P. Fendler
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Summary:Prostate-specific membrane antigen (PSMA)-ligand PET imaging provides unprecedented accuracy for whole-body staging of prostate cancer. As PSMA-ligand PET/CT is increasingly adopted in clinical trials and routine practice worldwide, a unified language for image reporting is urgently needed. We propose a molecular imaging TNM system (miTNM, version 1.0) as a standardized reporting framework for PSMA-ligand PET/CT or PET/MRI. miTNM is designed to organize findings in comprehensible categories to promote the exchange of information among physicians and institutions. Additionally, flowcharts integrating findings of PSMA-ligand PET and morphologic imaging have been designed to guide image interpretation. Specific applications, such as assessment of prognosis or impact on management, should be evaluated in future trials. miTNM is a living framework that evolves with clinical experience and scientific data.
Item Description:Published online Nov. 9, 2017
Gesehen am 28.11.2018
Physical Description:Online Resource
ISSN:2159-662X
DOI:10.2967/jnumed.117.198119

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