Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

Background: Glutathione-dependent catalysis is a metabolic adaptation to chemical challenges encountered by all life forms. In the course of evolution, nature optimized numerous mechanisms to use glutathione as the most versatile nucleophile for the conversion of a plethora of sulfur-, oxygen- or ca...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: Deponte, Marcel (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: May 2013
In: Biochimica et biophysica acta
Year: 2013, Jahrgang: 1830, Heft: 5, Pages: 3217-3266
ISSN:1878-2434
DOI:10.1016/j.bbagen.2012.09.018
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.bbagen.2012.09.018
Verlag, Volltext: https://linkinghub.elsevier.com/retrieve/pii/S0304416512002735
Volltext
Verfasserangaben:Marcel Deponte
Beschreibung
Zusammenfassung:Background: Glutathione-dependent catalysis is a metabolic adaptation to chemical challenges encountered by all life forms. In the course of evolution, nature optimized numerous mechanisms to use glutathione as the most versatile nucleophile for the conversion of a plethora of sulfur-, oxygen- or carbon-containing electrophilic substances.
Beschreibung:Published online: 1 October 2012
Gesehen am 29.11.2018
Beschreibung:Online Resource
ISSN:1878-2434
DOI:10.1016/j.bbagen.2012.09.018