Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes
Background: Glutathione-dependent catalysis is a metabolic adaptation to chemical challenges encountered by all life forms. In the course of evolution, nature optimized numerous mechanisms to use glutathione as the most versatile nucleophile for the conversion of a plethora of sulfur-, oxygen- or ca...
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
May 2013
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| In: |
Biochimica et biophysica acta
Year: 2013, Jahrgang: 1830, Heft: 5, Pages: 3217-3266 |
| ISSN: | 1878-2434 |
| DOI: | 10.1016/j.bbagen.2012.09.018 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.bbagen.2012.09.018 Verlag, Volltext: https://linkinghub.elsevier.com/retrieve/pii/S0304416512002735 
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| Verfasserangaben: | Marcel Deponte |
| Zusammenfassung: | Background: Glutathione-dependent catalysis is a metabolic adaptation to chemical challenges encountered by all life forms. In the course of evolution, nature optimized numerous mechanisms to use glutathione as the most versatile nucleophile for the conversion of a plethora of sulfur-, oxygen- or carbon-containing electrophilic substances. |
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| Beschreibung: | Published online: 1 October 2012 Gesehen am 29.11.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1878-2434 |
| DOI: | 10.1016/j.bbagen.2012.09.018 |