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Total synthesis of rhizopodin

Symmetry helps: The total synthesis of the potent actin-targeting C2-symmetric myxobacterial macrolide rhizopodin (see scheme) is accomplished by the convergent assembly of three building blocks of similar complexity, a concise macrocyclization strategy, and a late-stage introduction of the labile s...

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Bibliographic Details
Main Authors: Dieckmann, Michael (Author) , Kretschmer, Manuel (Author) , Li, Pengfei (Author) , Rudolph, Sven (Author)
Format: Article (Journal)
Language:English
Published: June 4, 2012
In: Angewandte Chemie. International edition
Year: 2012, Volume: 51, Issue: 23, Pages: 5667-5670
ISSN:1521-3773
DOI:10.1002/anie.201201946
Online Access:Verlag, Volltext: http://dx.doi.org/10.1002/anie.201201946
Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201201946
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Author Notes:Michael Dieckmann, Manuel Kretschmer, Pengfei Li, Sven Rudolph, Daniel Herkommer, and Dirk Menche
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Summary:Symmetry helps: The total synthesis of the potent actin-targeting C2-symmetric myxobacterial macrolide rhizopodin (see scheme) is accomplished by the convergent assembly of three building blocks of similar complexity, a concise macrocyclization strategy, and a late-stage introduction of the labile side chains.
Item Description:Gesehen am 18.12.2018
Physical Description:Online Resource
ISSN:1521-3773
DOI:10.1002/anie.201201946

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