Optimized serodiagnosis of Mycoplasma pneumoniae infections

Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients we...

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Bibliographic Details
Main Authors: Dumke, Roger (Author) , Herrmann, Richard (Author)
Format: Article (Journal)
Language:English
Published: 12 April 2012
In: Diagnostic microbiology and infectious disease
Year: 2012, Volume: 73, Issue: 2, Pages: 200-203
ISSN:1879-0070
DOI:10.1016/j.diagmicrobio.2012.02.014
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.diagmicrobio.2012.02.014
Verlag, Volltext: https://linkinghub.elsevier.com/retrieve/pii/S073288931200079X
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Author Notes:Roger Dumke, Andreas Strubel, Camille Cyncynatus, Hélène Nuyttens, Richard Herrmann, Christian Lück, Enno Jacobs
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Summary:Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients were confirmed by our immunoblotting approach having a specificity between 92.6% and 100%.
Item Description:Gesehen am 18.12.2018
Physical Description:Online Resource
ISSN:1879-0070
DOI:10.1016/j.diagmicrobio.2012.02.014