Cover Image

Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis

The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.

Saved in:
Bibliographic Details
Main Authors: Bucher, Delia (Author) , Frey, Felix (Author) , Kummer, Susann (Author) , Bergeest, Jan-Philip (Author) , Godinez, William J. (Author) , Kräusslich, Hans-Georg (Author) , Rohr, Karl (Author) , Schwarz, Ulrich S. (Author) , Boulant, Steeve (Author)
Format: Article (Journal)
Language:English
Published: 16 March 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-018-03533-0
Online Access:Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-03533-0
Verlag, Volltext: https://www.nature.com/articles/s41467-018-03533-0
Get full text
Author Notes:Delia Bucher, Felix Frey, Kem A. Sochacki, Susann Kummer, Jan-Philip Bergeest, William J. Godinez, Hans-Georg Kräusslich, Karl Rohr, Justin W. Taraska, Ulrich S. Schwarz, Steeve Boulant
Description
Summary:The sequence of structural and molecular events during clathrin-mediated endocytosis is unclear. Here the authors combine correlative microscopy and simple mathematical growth laws to demonstrate that the flat patch starts to curve when around 70% of the final clathrin content is reached.
Item Description:Gesehen am 14.01.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-03533-0

Similar Items