Thymustumoren: eine klinische Betrachtung
Introduction: Thymic tumors including thymomas, thymic carcinomas, and thymic carcinoid tumors are rare tumors with an incidence of 0.13/100,000. Materials and methods: A literature search was performed to identify recent findings on epidemiology, classification, and various therapeutic approaches....
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | German |
| Published: |
29. Januar 2016
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| In: |
Der Pathologe
Year: 2016, Volume: 37, Issue: 1, Pages: 91-106 |
| ISSN: | 1432-1963 |
| DOI: | 10.1007/s00292-016-0140-5 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1007/s00292-016-0140-5 Verlag, Volltext: https://doi.org/10.1007/s00292-016-0140-5 
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| Author Notes: | H. Grosch, H. Hoffmann, C.-A. Weis, M. Thomas |
| Summary: | Introduction: Thymic tumors including thymomas, thymic carcinomas, and thymic carcinoid tumors are rare tumors with an incidence of 0.13/100,000. Materials and methods: A literature search was performed to identify recent findings on epidemiology, classification, and various therapeutic approaches. Results: These tumors with a wide spectrum of histologic and biologic features may be clinically unapparent for a long time or show a very aggressive behavior with local invasion and distant metastases. Surgical resection is the mainstay in stage I and II thymomas, whereas in stage III thymomas and in thymomas with pleural dissemination surgery in context of a multimodal treatment should be discussed. Thymic tumors are chemoreactive. Targeted therapies show poor results and should only be considered in the palliative situation after failure of chemotherapy. Conclusion: The new TNM (T: tumor, N: node, M: metastasis) classification of thymic tumors will help to identify the best treatment options. |
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| Item Description: | Gesehen am 28.01.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1432-1963 |
| DOI: | 10.1007/s00292-016-0140-5 |