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Ventral striatum connectivity during reward anticipation in adolescent smokers

Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of...

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Bibliographic Details
Main Authors: Jollans, Lee (Author) , Banaschewski, Tobias (Author) , Flor, Herta (Author)
Format: Article (Journal)
Language:English
Published: 13 Apr 2016
In: Developmental neuropsychology
Year: 2016, Volume: 41, Issue: 1-2, Pages: 6-21
ISSN:1532-6942
DOI:10.1080/87565641.2016.1164172
Online Access:Verlag, Volltext: http://dx.doi.org/10.1080/87565641.2016.1164172
Verlag, Volltext: https://doi.org/10.1080/87565641.2016.1164172
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Author Notes:Lee Jollans, Cao Zhipeng, Ilknur Icke, Ciara Greene, Clare Kelly, Tobias Banaschewski, Arun L. W. Bokde, Uli Bromberg, Christian Büchel, Anna Cattrell, Patricia J. Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Michael N. Smolka, Henrik Walter, Gunter Schumann and Robert Whelan
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Summary:Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction.
Item Description:Gesehen am 07.02.2019
Physical Description:Online Resource
ISSN:1532-6942
DOI:10.1080/87565641.2016.1164172

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