Buchumschlag

Tobacco, occupation and non-transitional-cell carcinoma of the bladder: an international case-control study

Transitional-cell carcinoma is the dominant histological type of malignant tumors of the urinary bladder. There is limited information on risk factors for non-transitional-cell carcinoma (NTCC) of the bladder. We used data from 9 case-control studies on bladder cancer from 6 European countries to ex...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Fortuny, Joan (VerfasserIn) , Chang-Claude, Jenny (VerfasserIn) , Wahrendorf, Jürgen (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 08 November 1999
In: International journal of cancer
Year: 1999, Jahrgang: 80, Heft: 1, Pages: 44-46
ISSN:1097-0215
DOI:10.1002/(SICI)1097-0215(19990105)80:1<44::AID-IJC9>3.0.CO;2-8
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1002/(SICI)1097-0215(19990105)80:1<44::AID-IJC9>3.0.CO;2-8
Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/%28SICI%291097-0215%2819990105%2980%3A1%3C44%3A%3AAID-IJC9%3E3.0.CO%3B2-8
Volltext
Verfasserangaben:Joan Fortuny, Manolis Kogevinas, Jenny Chang‐Claude, Carlos-Alberto González, Martine Hours, Karl-Heinz Jöckel, Ulrich Bolm‐Audorff, Elsebeth Lynge, Andrea ‘T Mannetje, Stefano Porru, Ulrich Ranft, Consol Serra, Anastasia Tzonou, Jürgen Wahrendorf and Paolo Boffetta
Beschreibung
Zusammenfassung:Transitional-cell carcinoma is the dominant histological type of malignant tumors of the urinary bladder. There is limited information on risk factors for non-transitional-cell carcinoma (NTCC) of the bladder. We used data from 9 case-control studies on bladder cancer from 6 European countries to examine the association between NTCC, tobacco smoking and occupation. Information on 146 cases diagnosed with NTCC were matched by age, gender and study center to 727 non-cancer population or hospital controls and also with 722 transitional-cell-bladder-cancer controls. Lifetime smoking and occupational history were evaluated. A statistically significant excess risk for NTCC was observed for current smoking [odds ratio (OR) = 3.61, 95% confidence interval (CI) 2.08-6.28]. The risk increased with higher tobacco consumption (OR for highest tertile of pack-years = 7.01, 95% CI 3.60-13.66). The risks were higher for squamous-cell carcinomas than for other types of NTCC. Among major occupational groups, a significant excess risk was seen for field-crop and vegetable-farm workers (OR = 2.06, 95% CI 1.03-4.10). These results indicate that NTCC of the bladder is associated with smoking and specific occupations. The risk pattern seems to differ, in part, from that observed for transitional-cell carcinoma of the bladder. Int. J. Cancer 80:44-46, 1999. © 1999 Wiley-Liss, Inc.
Beschreibung:Gesehen am 11.02.2019
Beschreibung:Online Resource
ISSN:1097-0215
DOI:10.1002/(SICI)1097-0215(19990105)80:1<44::AID-IJC9>3.0.CO;2-8

Ähnliche Einträge