Super-resolved insights into human immunodeficiency virus biology

The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multic...

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Bibliographic Details
Main Authors: Hanne, Janina (Author) , Zila, Vojtech (Author) , Müller, Barbara (Author) , Kräusslich, Hans-Georg (Author)
Format: Article (Journal)
Language:English
Published: 10 May 2016
In: FEBS letters
Year: 2016, Volume: 590, Issue: 13, Pages: 1858-1876
ISSN:1873-3468
DOI:10.1002/1873-3468.12186
Online Access:Verlag, Volltext: http://dx.doi.org/10.1002/1873-3468.12186
Verlag, Volltext: https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.12186
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Author Notes:Janina Hanne, Vojtech Zila, Mike Heilemann, Barbara Müller and Hans-Georg Kräusslich
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Summary:The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multicolor imaging, make them ideally suited for visualization of native viruses and subviral structures within the complex environment of a host cell or organ, thus providing fundamentally new possibilities for investigating virus-cell interactions. Here, we review the use of super-resolution microscopy approaches to study virus-cell interactions, and discuss recent insights into human immunodeficiency virus biology obtained by exploiting these novel techniques.
Item Description:Gesehen am 12.02.2019
Physical Description:Online Resource
ISSN:1873-3468
DOI:10.1002/1873-3468.12186