Super-resolved insights into human immunodeficiency virus biology
The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multic...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 May 2016
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| In: |
FEBS letters
Year: 2016, Volume: 590, Issue: 13, Pages: 1858-1876 |
| ISSN: | 1873-3468 |
| DOI: | 10.1002/1873-3468.12186 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1002/1873-3468.12186 Verlag, Volltext: https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.12186 |
| Author Notes: | Janina Hanne, Vojtech Zila, Mike Heilemann, Barbara Müller and Hans-Georg Kräusslich |
| Summary: | The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multicolor imaging, make them ideally suited for visualization of native viruses and subviral structures within the complex environment of a host cell or organ, thus providing fundamentally new possibilities for investigating virus-cell interactions. Here, we review the use of super-resolution microscopy approaches to study virus-cell interactions, and discuss recent insights into human immunodeficiency virus biology obtained by exploiting these novel techniques. |
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| Item Description: | Gesehen am 12.02.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1873-3468 |
| DOI: | 10.1002/1873-3468.12186 |