Concise synthesis of acetal-protected syn 1,3-diols by a tandem hemiacetal formation/Tsuji-Trost reaction
Designed, developed, and applied: A novel domino sequence was used for the rapid assembly of acetal-protected syn 1,3-diols. The convergent synthesis of a polyol fragment of the macrolide antibiotic RK-397 demonstrates that this method is suitable for the rapid and stereoselective preparation of pol...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
15 August 2012
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| In: |
Angewandte Chemie. International edition
Year: 2012, Volume: 51, Issue: 37, Pages: 9425-9427 |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201203911 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1002/anie.201203911 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201203911 
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| Author Notes: | Liang Wang, Dirk Menche |
| Summary: | Designed, developed, and applied: A novel domino sequence was used for the rapid assembly of acetal-protected syn 1,3-diols. The convergent synthesis of a polyol fragment of the macrolide antibiotic RK-397 demonstrates that this method is suitable for the rapid and stereoselective preparation of polyketide-type diol motifs. |
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| Item Description: | Gesehen am 18.02.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201203911 |