Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure
Antibodies against merozoite antigens are key components of malaria immunity. The naturally acquired antibody response to these antigens is generally considered short-lived; however, the underlying mechanisms remain unclear. Prospective studies of travellers with different levels of prior exposure,...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
30 January 2019
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| In: |
BMC medicine
Year: 2019, Volume: 17 |
| ISSN: | 1741-7015 |
| DOI: | 10.1186/s12916-019-1255-3 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1186/s12916-019-1255-3 Verlag, Volltext: https://doi.org/10.1186/s12916-019-1255-3 
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| Author Notes: | Victor Yman, Michael T. White, Muhammad Asghar, Christopher Sundling, Klara Sondén, Simon J. Draper, Faith H.A. Osier and Anna Färnert |
| Summary: | Antibodies against merozoite antigens are key components of malaria immunity. The naturally acquired antibody response to these antigens is generally considered short-lived; however, the underlying mechanisms remain unclear. Prospective studies of travellers with different levels of prior exposure, returning to malaria-free countries with Plasmodium infection, offer a unique opportunity to investigate the kinetics and composition of the antibody response after natural infection. |
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| Item Description: | Gesehen am 25.02.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1741-7015 |
| DOI: | 10.1186/s12916-019-1255-3 |