Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity
Heterogeneity in gene expression and epigenetic states exists across individual cells. Here, the authors develop scCAT-seq, a technique for simultaneously performing ATAC-seq and RNA-seq within the same single cell.
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
28 January 2019
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| In: |
Nature Communications
Year: 2019, Volume: 10 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-08205-7 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-08205-7 Verlag, Volltext: https://www.nature.com/articles/s41467-018-08205-7 
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| Author Notes: | Longqi Liu, Chuanyu Liu, Andrés Quintero, Liang Wu, Yue Yuan, Mingyue Wang, Mengnan Cheng, Lizhi Leng, Liqin Xu, Guoyi Dong, Rui Li, Yang Liu, Xiaoyu Wei, Jiangshan Xu, Xiaowei Chen, Haorong Lu, Dongsheng Chen, Quanlei Wang, Qing Zhou, Xinxin Lin, Guibo Li, Shiping Liu, Qi Wang, Hongru Wang, J. Lynn Fink, Zhengliang Gao, Xin Liu, Yong Hou, Shida Zhu, Huanming Yang, Yunming Ye, Ge Lin, Fang Chen, Carl Herrmann, Roland Eils, Zhouchun Shang & Xun Xu |
| Summary: | Heterogeneity in gene expression and epigenetic states exists across individual cells. Here, the authors develop scCAT-seq, a technique for simultaneously performing ATAC-seq and RNA-seq within the same single cell. |
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| Item Description: | Gesehen am 28.02.2019 |
| Physical Description: | Online Resource |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-08205-7 |