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Shared heritability and functional enrichment across six solid cancers

Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degre...

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Main Authors: Jiang, Xia (Author) , Brenner, Hermann (Author) , Burwinkel, Barbara (Author) , Chang-Claude, Jenny (Author) , Hamann, Ute (Author) , Hoffmeister, Michael (Author) , Risch, Angela (Author)
Format: Article (Journal)
Language:English
Published: 25 January 2019
In: Nature Communications
Year: 2019, Volume: 10
ISSN:2041-1723
DOI:10.1038/s41467-018-08054-4
Online Access:Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-08054-4
Verlag, Volltext: https://www.nature.com/articles/s41467-018-08054-4
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Author Notes:Xia Jiang et al.#
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Summary:Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degree of common germline genetic basis.
Item Description:Gesehen am 28.02.2019
#Xia Jiang, Hermann Brenner, Barbara Burwinkel, Jenny Chang-Claude, Ute Hamann, Michael Hoffmeister, Angela Risch [und weitere]
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-08054-4

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