Buchumschlag

Shared heritability and functional enrichment across six solid cancers

Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Jiang, Xia (VerfasserIn) , Brenner, Hermann (VerfasserIn) , Burwinkel, Barbara (VerfasserIn) , Chang-Claude, Jenny (VerfasserIn) , Hamann, Ute (VerfasserIn) , Hoffmeister, Michael (VerfasserIn) , Risch, Angela (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 25 January 2019
In: Nature Communications
Year: 2019, Jahrgang: 10
ISSN:2041-1723
DOI:10.1038/s41467-018-08054-4
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-08054-4
Verlag, Volltext: https://www.nature.com/articles/s41467-018-08054-4
Volltext
Verfasserangaben:Xia Jiang et al.#
Beschreibung
Zusammenfassung:Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degree of common germline genetic basis.
Beschreibung:Gesehen am 28.02.2019
#Xia Jiang, Hermann Brenner, Barbara Burwinkel, Jenny Chang-Claude, Ute Hamann, Michael Hoffmeister, Angela Risch [und weitere]
Beschreibung:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-08054-4

Ähnliche Einträge