Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
GWAS have identified more than 500 genetic loci associated with blood lipid levels. Here, the authors report a genome-wide analysis of interactions between genetic markers and physical activity, and find that physical activity modifies the effects of four genetic loci on HDL or LDL cholesterol.
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Article (Journal) |
| Langue: | anglais |
| Publié: |
22 January 2019
|
| In: |
Nature Communications
Year: 2019, Volume: 10 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-08008-w |
| Accès en ligne: | Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-08008-w Verlag, Volltext: https://www.nature.com/articles/s41467-018-08008-w 
|
| Notes sur l'auteur: | Tuomas O. Kilpeläinen et al.# |
| Résumé: | GWAS have identified more than 500 genetic loci associated with blood lipid levels. Here, the authors report a genome-wide analysis of interactions between genetic markers and physical activity, and find that physical activity modifies the effects of four genetic loci on HDL or LDL cholesterol. |
|---|---|
| Description: | #Tuomas O. Kilpeläinen, Jost B. Jonas [und weitere] Gesehen am 04.03.2019 |
| Description matérielle: | Online Resource |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-018-08008-w |