Management of pulmonary hypertension in neonates with congenital diaphragmatic hernia

<p>Pulmonary hypertension associated with congenital diaphragmatic hernia is still one of the major challenges in neonatal intensive care units. Several relevant pathways in its pathogenesis have been described and studied, but the absence of well-designed randomized controlled trials and the...

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Bibliographic Details
Main Authors: Vijfhuize, Sanne (Author) , Schaible, Thomas (Author) , Krämer, Ulrike (Author)
Format: Article (Journal)
Language:English
Published: 31.Oktober 2012
In: European journal of pediatric surgery
Year: 2012, Volume: 22, Issue: 5, Pages: 374-383
ISSN:1439-359X
DOI:10.1055/s-0032-1329531
Online Access:Verlag, Volltext: http://dx.doi.org/10.1055/s-0032-1329531
Verlag, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1329531
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Author Notes:S. Vijfhuize, T. Schaible, U. Kraemer, T.E. Cohen-Overbeek, D. Tibboel, I. Reiss
Description
Summary:<p>Pulmonary hypertension associated with congenital diaphragmatic hernia is still one of the major challenges in neonatal intensive care units. Several relevant pathways in its pathogenesis have been described and studied, but the absence of well-designed randomized controlled trials and the scattered data on the pharmacokinetics and pharmacodynamics of most of the drugs used in these patients hamper progress significantly. This review aims to give an overview of current management strategies in the antenatal and neonatal phase, and provides founded clinical recommendations.</p>
Item Description:Gesehen am 07.03.2019
Physical Description:Online Resource
ISSN:1439-359X
DOI:10.1055/s-0032-1329531