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Given and acquired risk factors in cognitive decline, the development of Mild Cognitive Impairment, and Alzheimer’s Disease: results of a prospective, population-based, longitudinal study

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In this dissertation, three articles on the relative roles of given and acquired risk factors in cognitive aging, the development of mild cognitive impairment and Alzheimer's disease are discussed. Data are derived from the Interdisciplinary Longitudinal Study of Adult Aging (ILSE). In the firs...

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Bibliographic Details
Main Author: Degen, Christina (Author)
Format: Book/Monograph Thesis
Language:English
Published: Heidelberg 2016
DOI:10.11588/heidok.00022041
Subjects:
Hochschulschrift
Online Access:Resolving-System, kostenfrei, Volltext: http://dx.doi.org/10.11588/heidok.00022041
Resolving-System, kostenfrei, Volltext: http://nbn-resolving.de/urn:nbn:de:bsz:16-heidok-220415
Resolving-System, Volltext: https://nbn-resolving.org/urn:nbn:de:bsz:16-heidok-220415
Langzeitarchivierung Nationalbibliothek, Volltext: http://d-nb.info/1180736265/34
Verlag, kostenfrei, Volltext: http://www.ub.uni-heidelberg.de/archiv/22041
Resolving-System, Unbekannt: https://doi.org/10.11588/heidok.00022041
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Author Notes:presented by Christina Degen ; Dean: Prof. Dr. Birgit Spinath ; Advisor: Prof. Dr. med. Johannes Schröder
Description
Summary:In this dissertation, three articles on the relative roles of given and acquired risk factors in cognitive aging, the development of mild cognitive impairment and Alzheimer's disease are discussed. Data are derived from the Interdisciplinary Longitudinal Study of Adult Aging (ILSE). In the first article, the role of cholesterol Levels in midlife and during aging as well as the APOE genotype are considered. In the second article, the contribution of the COMT genotype on cognitive aging is investigated. In a third article, the role of Diabetes mellitus Type II on cognitive aging is discussed. I conclude that Lifestyle factors in midlife are more important than given risk factors (e.g. genes) for risk of pathological aging.
Physical Description:Online Resource
DOI:10.11588/heidok.00022041

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