Repurposing of promoters and enhancers during mammalian evolution

Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing...

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Bibliographic Details
Main Authors: Carelli, Francesco N. (Author) , Kaessmann, Henrik (Author)
Format: Article (Journal)
Language:English
Published: 04 October 2018
In: Nature Communications
Year: 2018, Volume: 9
ISSN:2041-1723
DOI:10.1038/s41467-018-06544-z
Online Access:Verlag, Volltext: https://doi.org/10.1038/s41467-018-06544-z
Verlag, Volltext: https://www.nature.com/articles/s41467-018-06544-z
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Author Notes:Francesco N. Carelli, Angélica Liechti, Jean Halbert, Maria Warnefors, Henrik Kaessmann
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Summary:Enhancers and promoters are different types of regulatory elements with shared architectural and functional features. Here the authors perform integrated cross-mammalian analyses of DNase hypersensitivity, chromatin modification and transcriptional data, to provide evidence of regulatory repurposing during evolution.
Item Description:Gesehen am 29.03.2019
Physical Description:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-06544-z